Charbonnel_inra_image
nathalie.charbonnel@inrae.fr

Nathalie CHARBONNEL

Research Director, INRAE

Area(s)

My research in health ecology focuses broadly on the interactions between small mammals (rodents, insectivores, bats) and pathogens. It aims to describe these interactions and their variability across time and space, and to understand the ecological mechanisms that govern their evolution. As part of my work on zoonoses and the risks of emerging diseases, I focus on characterising reservoirs and zoonotic agents, analysing the macro- and micro-evolutionary processes that shape the diversity of reservoir/pathogen interactions, and assessing the impact of co-infections and microbial flora on the susceptibility of small mammals to certain potentially zoonotic pathogens. I am conducting this research within multi- and trans-disciplinary projects to co-develop small mammal management strategies that are ‘win-win’ for biodiversity conservation and public health.

 

Keywords: zoonoses, health ecology, rodents, mammals.

Last publications
Garona J., Berard* A., Tatard C., Kwasiborski A., Gauthier P., Ag Atteynine S., Hourdel V., Eusebe A., Diagne C., Caro V., Brouat C., Charbonnel N., Sauvage V., Granjon L. & Castel G. 2025. Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023). One Health 20 : 101085. (https://dx.doi.org/10.1016/j.onehlt.2025.101085)
Berard* A., Pradel J., Charbonnel N. & Galan M. 2025. Spider webs, soil or leaf swabs to detect environmental DNA from terrestrial vertebrates: what is the best substrate?. Molecular Ecology Resources 25 : e70037. (https://dx.doi.org/10.1111/1755-0998.70037)
Beaubaton R., Revel J., Pigeyre L., Bollore K., Lepeule A., Mocq J., de Franceschi C., Pradel J., Perrin Y., Gomis D., Ducousso M., Virolle L., Chenet B., Castel G., Charmantier A., Charbonnel N., Lacour G., Courot O., Mignotte A. & Simonin Y. 2025. Tracking the urban spread of Usutu virus in southern France: Detection across biological and environmental matrices. PLoS Neglected Tropical Diseases 19 : e0013506. (https://dx.doi.org/10.1371/journal.pntd.0013506)
Arnal A., Gozlan R.E., Charbonnel N., Bouilloud* M., Chaves A., Gauthier-Clerc M., Vigueras-Galván A.L., Arnathau C., Roiz D., Bento A.I., Morand S., Walzer C., Suzán G., Sarmiento Silva R.E. & Roche B. 2025. Leveraging small biodiversity reserves to prevent zoonotic disease: insights from dilution effect and pathogen adaptation theories. Disease Biology, Genetics, and Socioecology : 6. (https://dx.doi.org/10.53941/dbgs.2025.100006)
Garcia-Lopez M., Lurier T., Bouilloud* M., Pradel J., Tatard C., Sepulveda D., Anfray G., Dussert J., Bourhy P., Charbonnel N. & Djelouadji Z. 2024. Prevalence, genetic diversity and eco-epidemiology of pathogenic Leptospira species in small mammal communities in urban parks Lyon city, France. PLoS One 19 : e0300523. (https://dx.doi.org/10.1371/journal.pone.0300523)
Folkertsma R., Charbonnel N., Henttonen H., Heroldova M., Huitu O., Kotlik P., Manzo E., Paijmans J.L.A., Plantard O., Sandor A.D., Hofreiter M. & Eccard J.A. 2024. Genomic signatures of climate adaptation in bank voles. Ecology and Evolution 14 : e10886. (https://dx.doi.org/10.1002/ece3.10886)
Bouilloud* M., Galan M., Pradel J., Loiseau A., Ferrero J., Gallet R., Roche B. & Charbonnel N. 2024. Exploring the potential effects of forest urbanization on the interplay between small mammal communities and their gut microbiota. Animal Microbiome 6 : 16. (https://dx.doi.org/10.1186/s42523-024-00301-y)
Arpin I., Massart C., Bourret V., Castel G., Colombo V.C., Eccard J., Firozpoor J., Grzybek M., Henttonen H.A., Leirs H., McManus A., Roche B., Sironen T., Sluydts V., Stuart P., Zintl A. & Charbonnel N. 2024. Achieving inter- and transdisciplinarity in Ecohealth: insights from a rodent-borne disease project in a polycrisis era. Frontiers in Veterinary Science 11 : 1235183. (https://dx.doi.org/10.3389/fvets.2024.1235183)
Alburkat H., Smura T., Bouilloud* M., Pradel J., Anfray G., Berthier K., Dutra L., Loiseau A., Niamsap T., Olander V., Sepulveda D., Venkat V., Charbonnel N., Castel G. & Sironen T. 2024. Evolution and genetic characterization of Seoul virus in wild rats Rattus norvegicus from an urban park in Lyon, France 2020-2022. PLoS Neglected Tropical Diseases 18 : e0012142. (https://dx.doi.org/10.1371/journal.pntd.0012142)
Abbate J., Galan M., Razzauti M., Sironen T., Voutilainen L., Henttonen H., Gasqui P., Cosson J.-F. & Charbonnel N. 2024. Pathogen community composition and co-infection patterns in a wild community of rodents. Peer Community Journal 4 : e14. (https://dx.doi.org/10.1101/2020.02.09.940494)