KINCAID-SMITH Julien
julien.kincaid-smith@ird.fr

Julien KINCAID-SMITH

Research Manager, IRD

Area(s)

Julien KINCAID-SMITH joined us on 1 November 2023. His research project aims to develop an integrative “One Health” approach to schistosomiasis, a disease recently recognised as zoonotic, in order to achieve several objectives:

  1. to determine, at a local scale, the spatiotemporal dynamics of schistosome infection at the human-animal-environment interface and gene flow between parasite species,
  2. to identify the ecological, evolutionary and social factors associated with the zoonotic transmission of schistosomes,
  3. to assess whether mass treatment of human populations has implications in terms of changes in parasite hosts and parasite sensitivity to the drug.

 

Julien will initially carry out his project in Senegal, at the study sites he worked on during his postdoctoral research at the CBGP.

Last publications
Luviano-Aparicio N., Mathieu-Begne E., Kincaid-Smith J., Rey O., Picard M., Chaparro C., Allienne J.F., Rognon A., Polack B., Vallee I., Thomas M., Boissier J. & Toulza E. 2026. Transcriptomic plasticity in hybrid schistosomes can contribute to their zoonotic potential. Philosophical Transactions of the Royal Society B: Biological Sciences 381 : 20240534. (https://dx.doi.org/10.1098/rstb.2024.0534)
Savassi B., Kincaid-Smith J., Courtin D., Ibikounle M., Toulza E., Galinier R., Milet J., Gineau L., Garcia A., Houngnihin R., Blin M., Brouat C., Liang S. & Boissier J. 2026. African zoonotic schistosomiasis: a paradigm shift. Philosophical Transactions of the Royal Society B: Biological Sciences 381 : 20240522. (https://dx.doi.org/10.1098/rstb.2024.0522)
Kincaid-Smith J., Savassi B., Senghor B., Diagne C., Niang Y., Kane M., Tatard C., Brouat C. & Granjon L. 2024. African schistosomes in small mammal communities: Perspectives from a spatio-temporal survey in the vicinity of Lake Guiers, Senegal. PLoS Neglected Tropical Diseases 18 : e0012721. (https://dx.doi.org/10.1371/journal.pntd.0012721)
Mathieu-Begne E., Kincaid-Smith J., Chaparro C., Allienne J.F., Rey O., Boissier J. & Toulza E. 2024. Schistosoma haematobium and Schistosoma bovis first generation hybrids undergo gene expressions changes consistent with species compatibility and heterosis. PLoS Neglected Tropical Diseases 18 : e0012267. (https://dx.doi.org/10.1371/journal.pntd.0012267)
Huguenin A., Kincaid-Smith J., Depaquit J., Boissier J. & Ferte H. 2023. MALDI-TOF: A new tool for the identification of Schistosoma cercariae and detection of hybrids. PLoS Neglected Tropical Diseases 17 : e0010577. (https://dx.doi.org/10.1371/journal.pntd.0010577)
Onyekwere A.M., De Elias-Escribano A., Kincaid-Smith J., Dametto S., Allienne J.F., Rognon A., Bargues M.D. & Boissier J. 2022. Mating interactions between Schistosoma bovis and S. mansoni and compatibility of their F1 progeny with Biomphalaria glabrata and Bulinus truncatus. Microorganisms 10 : 1251. (https://dx.doi.org/10.3390/microorganisms10061251)
Kincaid-Smith J., Tracey A., de Carvalho Augusto R., Bulla I., Holroyd N., Rognon A., Rey O., Chaparro C., Oleaga A., Mas-Coma S., Allienne J.-F., Grunau C., Berriman M., Boissier J. & Toulza E. 2021. Morphological and genomic characterisation of the Schistosoma hybrid infecting humans in Europe reveals admixture between Schistosoma haematobium and Schistosoma bovis. PLOS Neglected Tropical Diseases 15 : e0010062. (https://dx.doi.org/10.1371/journal.pntd.0010062)