The program BOTTLENECK computes for each population sample and for each locus the distribution of the heterozygosity expected from the observed number of alleles (k), given the sample size (n) under the assumption of mutation-drift equilibrium. This distribution is obtained through simulating the coalescent process of n genes under three possible mutation models.
Jean-Marie Cornuet and Gordon Luikart
Cornuet J.M. and Luikart G., 1997 Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data. Genetics, 144: 2001-2014.
Code written with Delphi 4.0® for Windows95® by Sylvain Piry
By Jean-Marie Cornuet on 1999-02-16
